Breast Cancer with Brain Metastases Treatment: Restoring Hope Through ECCT

Patient: Tan Chui Eng, 73, Bintulu, Malaysia

Diagnosis: Breast Cancer with Brain Metastases

When Mdm Tan Chui Eng was diagnosed with advanced breast cancer in 2019, she responded well to chemotherapy and hormonal therapy. But in 2024, her condition took a serious turn when cancer had spread to her brain. Despite undergoing brain radiotherapy and continuing treatment with Kryxana and Faslodex, she became non-ambulatory and required constant care.

In February 2025, her tumour markers remained high:

• CEA: 5.7 ng/mL

• CA 15-3: 40.2 U/mL

These values signalled that the cancer was still active in her body, despite months of targeted therapy.

Then, in mid-April 2025, her family introduced ECCT as an additional approach to Kryxana and Faslodex, not to replace, but to support her ongoing medical regimen as her Breast Cancer with Brain Metastases Treatment. ECCT sessions were conducted daily at home using a specialised blanket and helmet setup tailored for her condition.

In just 3 months of combination treatment, the results were remarkable. By July 2025:

• CEA dropped to 2.0 ng/mL

• CA 15-3 reduced to 18.1 U/mL

Both tumour markers were back within normal range, for the first time in many months.

Period	Key Treatments	Tumour Marker Trend	Notes
Aug 2024 – Jan 2025	Brain radiotherapy (Aug), Kryxana (ongoing), Faslodex (started ~Oct 2024)	Tumour marker data not available	No CEA/CA 15-3 data to track systemic cancer burden
Feb – Mar 2025	Kryxana + Faslodex (not started ECCT yet)	CEA: 5.7 → 4.5 CA 15-3:  40.2 → 35.0	Mild improvement over 1 month. Suggests slow biochemical response.
Mid-April – July 2025	Kryxana + Faslodex + ECCT started	CEA: 4.5 → 2.0CA 15-3: 35.0 → 18.1	Steady and sharper decline suggesting faster body response. Normalized marker by July.

 Her family saw more than just lab numbers. She was more alert, memory better and sleeping better. Her oncology as well noticed that her mental state and memory is stabilized. Though still physically weak, she had regained a sense of peace — and they had regained time with her. Tan Chui Eng’s journey is a powerful reminder that in complex, late-stage cancer, even small windows of progress matter.