Clinically Meaningful Breast Wound Resolution in Advanced Breast Cancer

United Kingdom, Stage 4 Breast Wound Resolution in Advanced Breast Cancer. She was diagnosed with stage 4 invasive breast cancer and presented with a large breast wound associated with persistent discharge. The wound required frequent dressing changes and ongoing monitoring due to the risk of infection, skin breakdown, and impaired healing. At baseline, the discharge volume was significant, and the surrounding tissue showed signs of inflammation and poor wound stability.

The wound had a substantial impact on her functional status and quality of life. She experienced discomfort with movement, sleep disturbance, and pain that affect her daily activities. Continuous exudate management was necessary, contributing to physical fatigue and psychological distress over prolonged periods.

However, progressive changes were subsequently observed upon starting of ECCT for a couple of months. There was a marked reduction in discharge volume, improvement in local tissue condition, and decreased inflammation of the periwound area after 3 months of usage. Dressing frequency was gradually reduced as wound stability improved.

Over time, the wound showed clear evidence of healing, with near-complete resolution of discharge and restoration of skin integrity at her breast area. These changes correlated with improved comfort, enhanced quality of life, and reduced care burden. She reported improved a significant reduction in anxiety related to wound leakage and daily wound management.

Alongside her recovery of scan with remarkable reduced tumour burden, the recovery of the breast wound represented a clinically meaningful outcome. The improvement contributed to enhanced quality of life and functional independence, demonstrating a favorable local response in a previously refractory wound condition.