Advanced Lung Cancer: How ECCT + Chemotherapy Helped Reduce Tumor Size by 70–80%

For five months, he had been dealing with a persistent, unrelenting cough that never seemed to improve. A CT scan in early July revealed a lung mass larger than 8 cm, with spread to the lymph nodes around the trachea and airways, along with fluid buildup (pleural effusion) in the right lung. Based on these findings, his condition was already considered clinically as Advanced Lung Cancer.

The biopsy confirmed adenocarcinoma, and further testing showed that both EGFR and ALK mutations were negative, leaving no suitable targeted therapies available. He began chemotherapy in September and added ECCT to his treatment in mid-October. Remarkably, the persistent cough—present for months and still ongoing during chemotherapy, finally stopped within just a few days after starting ECCT.

In cases with unknown mutation profiles or unclear tumor grades, combining ECCT with non-targeted chemotherapy is often used to speed up tumor shrinkage and reduce inflammation. This combination typically helps symptoms such as chronic coughing resolve faster than relying on chemotherapy alone or ECCT alone.

A follow-up CT scan performed one month after starting ECCT showed significant improvement, with the tumor shrinking by approximately 70–80% in volume compared with the scan taken four months earlier. Overall, his condition remained relatively good and stable.